Showing posts with label Growth. Show all posts
Showing posts with label Growth. Show all posts

Thursday, April 7, 2011

Growth In Prevalence Of Eating Disorders Prompts Care UK To Expand Service Offering


Main Category: Eating Disorders
Article Date: 09 Feb 2011 - 0:00 PST window.fbAsyncInit = function() { FB.init({ appId: 'aa16a4bf93f23f07eb33109d5f1134d3', status: true, cookie: true, xfbml: true, channelUrl: 'http://www.medicalnewstoday.com/scripts/facebooklike.html'}); }; (function() { var e = document.createElement('script'); e.async = true; e.src = document.location.protocol + '//connect.facebook.net/en_US/all.js'; document.getElementById('fb-root').appendChild(e); }()); email icon email to a friend   printer icon printer friendly   write icon opinions
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A marked national growth in acute, severe and enduring cases of eating disorders has prompted Care UK to expand its service offering with the acquisition of a renowned acute hospital that specialises in the treatment of children and adolescents suffering from anorexia, bulimia and similar conditions.

"We plan to extend this approach to Rhodes Farm to add to its established reputation for successful weight restoration and psychological intervention and so develop a market- leading service that makes a real difference to the young person's perception of themselves and to their future quality of life."

Care UK, which already runs two successful intensive rehabilitation units at Althea Park in Gloucestershire, has completed the purchase of the Rhodes Farm Clinic which operates from Mill Hill in London and was formerly owned and run by Dr Dee Dawson.

Care UK sees Rhodes Farm as an excellent complementary addition to its existing eating disorder service which focuses on a highly successful rehabilitation and recovery approach. This approach places the emphasis on psychological and social interventions and on treating the psychological issues which underlie the eating disorder, rather than focusing exclusively on weight gain.

Rhodes Farm, as an acute facility, will continue to help young people attain a healthy weight in order to enable them to go on to engage effectively in a psychological and social therapeutic programme. More importantly they also provide a range of therapies designed to help young people and their families manage and understand eating disorders. Last year 87% of clients discharged were successfully supported in the community, preventing the need for readmission.

Care UK's Managing Director for Mental Health, Dr Alison Rose-Quirie said: "Care UK offers a residential alternative to hospital treatment for people who have already tried other routes many times. A significant number of people with eating disorders get stuck in a 'revolving door' cycle of treatment and relapse. This pattern can seriously impact upon a person's life and identity, as well as their physical and mental health. Our programmes are specifically designed to help young women with eating disorders bring about life change and not just weight change. We actively support people to rediscover an identity outside of their illness, an approach which can have dramatic positive results."

"We plan to extend this approach to Rhodes Farm to add to its established reputation for successful weight restoration and psychological intervention and so develop a market- leading service that makes a real difference to the young person's perception of themselves and to their future quality of life."

Source:
Care UK

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Tuesday, March 22, 2011

S. mutans Biofilm Growth Inhibited By Biodegradable Tooth-Binding Micelles


Main Category: Dentistry
Also Included In: Infectious Diseases / Bacteria / Viruses
Article Date: 21 Mar 2011 - 1:00 PDT window.fbAsyncInit = function() { FB.init({ appId: 'aa16a4bf93f23f07eb33109d5f1134d3', status: true, cookie: true, xfbml: true, channelUrl: 'http://www.medicalnewstoday.com/scripts/facebooklike.html'}); }; (function() { var e = document.createElement('script'); e.async = true; e.src = document.location.protocol + '//connect.facebook.net/en_US/all.js'; document.getElementById('fb-root').appendChild(e); }()); email icon email to a friend   printer icon printer friendly   write icon opinions
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During the 89th General Session & Exhibition of the International Association for Dental Research, held in conjunction with the 40th Annual Meeting of the American Association for Dental Research and the 35th Annual Meeting of the Canadian Association for Dental Research, lead researcher F. Cheni held an oral presentation on a research study titled "Biodegradable Tooth-binding Micelles Inhibit Streptococcus mutans (S. mutans) Biofilm Growth."

This research was performed under the objective to develop tooth-binding micelles(TBM) using peptide based biodegradable tooth-binding moieties that can effectively bind to the tooth surface to provide prolonged drug retention in the oral cavity, but can also safely detach from the tooth by gradual degradation of the peptide. Di-phosphoserine, tetra-phosphoserine and hexa-phosphoserine peptides were synthesized using a standard solid phase peptide synthesis method. These oligopeptides were conjugated to Pluronic P123 copolymer using a click reaction.

The tooth-binding micelle was prepared by self-assembly of the modified Pluronics with the antimicrobial agent triclosan. The binding kinetics of TBMs on hydroxyapatite (HA) particles was evaluated using a UV spectrophotometer. For in vitro biofilm prevention studies, HA discs were pretreated with different TBM formulations prior to inoculation with S. mutans UA159, and subsequent biofilm formation was assessed. Biofilm growth was measured by calculating the colony forming units (CFU) recovered per disc. Specific differences between the log-CFU/biofilm of each experimental group were analyzed using the Student t-test. A p-value of< 0.05="" was="" considered="" as="" statistically="" significant.="">

The binding kinetics of TBMs on HA particles were found to be fast (< 1="" min).="" higher="" binding="" capacity="" was="" achieved="" using="" tetra-="" and="" hexa-phosphoserine="" as="" binding="" moieties.="" in="" biofilm="" prevention="" study,="" the="" tbm="" treated="" groups="" all="" showed="" significantly="" lower="" cfu="" (2="" to="" 4-log="" reduction,=""><0.05) per="" ha="" disc="" compared="" to="" the="" control="" groups.="">

Notes:

This work was supported in part by NIH grants AR053325 (DW) and AI038901 (KWB).

This is a summary of abstract #3027 "Biodegradable Tooth-binding Micelles Inhibit Streptococcus mutans Biofilm Growth," presented by F. Cheni at the San Diego Convention Center.

Source:
Ingrid L. Thomas
International & American Association for Dental Research


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Note: Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a health care professional. For more information, please read our terms and conditions.

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